Well being continues to ascertain itself as one of many fundamental differentiating components for profitability in pig manufacturing firms. Ailments scale back the overall variety of weaned piglets, improve mortality, and deteriorate feed conversion charges, including to elevated well being, logistical, and labor prices related to managing the state of affairs. The distinction in manufacturing prices between farms, manufacturing flows, or firms with important well being challenges and people much less affected usually exceeds the historic revenue margin of the trade. Because of this in much less favorable market situations, the profitability and financial sustainability of sure farms, flows, or firms could also be at critical threat. Moreover, using antibiotics to deal with gathered illnesses in pig populations is more and more restricted.
The foundations of a complete well being enchancment program in a pig manufacturing system embody:
- Prevention (biosecurity) to attenuate the danger of introducing infectious brokers
- Stabilization (management) to mitigate the influence of present illnesses
- Eradication of pathogens that may be eradicated at an affordable value
To attain this, veterinarians and producers have a number of well being interventions accessible, reminiscent of biosecurity, immunizations, strategic remedy, all-in/all-out circulate, batch farrowing administration, herd closure, and acclimatization of substitute animals, which needs to be utilized in line with the precise context.
Ailments reminiscent of PRRS, swine influenza, enzootic pneumonia (Mycoplasma hyopneumoniae), or swine dysentery (Brachyspira hyodysenteriae) can usually be eradicated by way of a correct mixture of the aforementioned methods. Nevertheless, different excessive pathogenic strains of brokers—reminiscent of Actinobacillus pleuropneumoniae, Streptococcus suis, Glaesserella parasuis, or Escherichia coli—can’t be eradicated from pig populations with out resorting to extra radical methods reminiscent of depopulation–repopulation or cesarean derived-colostrum disadvantaged piglet era.
When a number of of those extra resilient brokers trigger important losses, or when a number of high-impact illnesses coexist, a scientific evaluation needs to be performed to find out whether or not depopulation–repopulation is probably the most applicable software to implement.

Determine 1. Choice tree to evaluate the feasibility of finishing up a depopulation–repopulation undertaking. Is depopulation-repopulation of curiosity to my farm?
Planning
Depopulation and repopulation of pig farms contain the entire removing of present animals, adopted by thorough washing and disinfection of the services, and the next introduction of animals with larger well being standing. The expertise gathered from 30 depopulation–repopulation tasks might be summarized in 5 essential factors that decide the success of the method:
- Choice-making course of to justify and execute the undertaking. This section requires thorough analysis and a structured deliberation course of to construct consensus amongst administration, manufacturing, and well being groups earlier than initiating the undertaking. Key features to contemplate embody:
- Estimating the present financial influence of current illnesses, or projecting value reductions after reaching the specified well being standing.
- Evaluating the danger of reintroducing the pathogens focused for elimination or estimating the period for which the improved well being standing might be maintained. Most economically essential pathogens reminiscent of Brachyspira hyodysenteriae, Actinobacillus pleuropneumoniae, Streptococcus suis or Glaesserella parasuis might be prevented with a primary biosecurity program. Even in farms situated in excessive pig density areas, as a result of the oblique transmission of these brokers is much less doubtless.
- Making certain the supply of substitute gilts—each initially and sooner or later—that meet the required well being standing and possess aggressive genetic potential.
- Assessing the sensible feasibility of the undertaking, contemplating the supply of certified personnel, appropriate services, and adequate logistical help.
- Supply of substitute animals with superior well being standing. The corporate should have strong ensures relating to the well being standing of the supply farm for the substitute gilts. This farm have to be free from high-impact epidemic brokers reminiscent of PRRS, Actinobacillus pleuropneumoniae, Mycoplasma hyopneumoniae, and Brachyspira hyodysenteriae. As well as, the range and scientific influence of endemic brokers reminiscent of Streptococcus suis, Glaesserella parasuis, Escherichia coli, or PCV2 have to be completely understood.
- Administration of gilt improvement and breeding in an exterior facility. Within the absence of an exterior facility for gilt improvement and breeding, a depopulation–repopulation undertaking would contain a 20 to 22-week interruption in weaned piglet manufacturing, which most often renders the undertaking economically unviable. To attenuate this manufacturing loss, it is suggested to make use of a biosecure exterior facility to collect, race, and breed the substitute gilts so they’re able to enter the farm on the applicable time (Fig. 2). This technique can scale back the non-productive interval to 4–6 weeks, a good portion of which might be recovered because of the improved productive efficiency of the brand new animals.
Determine 2. Timeline and animal circulate diagram throughout the depopulation–repopulation course of.
- Process for emptying and decontaminating the services. 5 or 6 weeks earlier than starting breeding on the exterior farm, breeding is halted on the farm that shall be depopulated. From that time on, all weaned sows are despatched to slaughter, and the method of emptying, cleansing, and disinfecting the farm begins, which can prolong over the next 20 weeks. Weekly exercise planning is crucial to make sure the removing of 100% of natural matter from all areas, correct administration of slurry pits, execution of obligatory upkeep and renovations, pest management, cleansing of showers, storage areas, workplace, and environment of the farm, in addition to systematic inspection of every part. Every firm could have particular protocols for cleansing, degreasing, and disinfecting, however success relies upon totally on meticulous and constant implementation at each stage of the undertaking.
- Introduction and beginning of the brand new inhabitants. As soon as the overall removing of natural matter, mud, and biofilm has been verified, and the right utility of disinfectants on the indicated focus confirmed, together with the absence of moisture within the services, the period of the “sanitary down time” turns into a much less essential issue for the success of the undertaking. In some instances, using sentinel animals is justified to validate the absence of infectious brokers earlier than introducing the brand new inhabitants. After an funding of this magnitude, it’s essential to make sure that the transport items used pose minimal sanitary threat. The entry of the sows needs to be staggered, beginning with these closest to breeding or farrowing, and ending with the final sows bred on the exterior rearing facility, so as to facilitate embryo implantation. To make sure profitable manufacturing within the new inhabitants, it’s important to contemplate coaching the sows on the automated feeding system throughout gestation, in addition to cautious administration of physique situation throughout the exterior rearing section.
Conclusion
Depopulation-repopulation is an efficient technique for breaking the cycles of high-impact illness transmission. Its correct implementation not solely improves herd well being standing but in addition restores manufacturing effectivity and long-term profitability. Nevertheless, the success of the method relies on rigorous planning, meticulous execution, and a previous technical-economic analysis that justifies its feasibility. Confronted with an more and more difficult well being setting and a extra aggressive market, establishing probably the most cost-effective technique could make the distinction between the sustainability or failure of a swine enterprise.