Goal: This research investigated the results of a phytogenic feed additive (PFA) containing a mix of herbs, plant extracts and important oils from the Lamiaceae, Schisandraceae, Zingiberaceae and Fabaceae households on the fecal rating, intestinal histomorphology and fecal excretion of F4-fimbriated enterotoxigenic Escherichia coli (F4-ETEC) in post-weaning piglets.
Strategies: Thirty 31-day-old weaned piglets have been randomly allotted to a few remedy teams. The constructive management (PC) group acquired colistin through consuming water from d 8 to 14 post-weaning and the identical basal eating regimen because the detrimental management (NC) group; the remedy group acquired the basal eating regimen with PFA supplementation (1 g/kg of feed). The experiment lasted 21 days. At day 9 post-weaning, all piglets have been orally administered 3.0 × 1010 CFU/piglet of the F4-ETEC pressure.
Outcomes: The PC piglets had larger fecal consistency than the NC and PFA piglets. PFA supplementation resulted in a decrease proportion of piglets excreting F4-ETEC within the feces on days 4–7 post-challenge than within the NC group (p < 0.05) however a better proportion versus the PC group on day 3–7 post-challenge (p < 0.05). The variety of goblet cells (GCs) within the jejunum of the PFA piglets was larger than the NC and PC piglets (p < 0.01). The GC density within the jejunum of the PFA piglets was bigger than within the PC piglets (p < 0.05) and much like the NC piglets (p > 0.10). Mucus thickness within the jejunum of the PFA piglets was much like the NC piglets and PC piglets (p > 0.10).
Conclusion: PFA supplementation to the F4-ETEC-challenged piglets decreased the prevalence of fecal E. coli excretion and improved jejunal histomorphology.
Alberto T-P, Keiner A, Le Gall M, Molist F, Guan X, Middelkoop A, Jiménez-Moreno E, Balfagón A, Mantovani G, Nofrarías M, et al. Impression of a Phytogenic Feed Additive on Diarrhea Incidence, Intestinal Histomorphology and Fecal Excretion of F4-Fimbriated Enterotoxigenic Escherichia coli in Submit-Weaning Piglets. Stresses. 2025; 5(1):8. https://doi.org/10.3390/stresses5010008
